The heart healthy reputation of epigallocatechin gallate (EGCG), the main extract from green tea, may be due in part to improvement in blood flow through the vessels, suggests a clinical trial from the US.
"EGCG acutely improves endothelial function in humans with coronary artery disease, and may account for a portion of the beneficial effects of flavonoid-rich food on endothelial function," wrote the authors in the Journal of the American College of Nutrition.
The researchers, led by Michael Widlansky from Boston University School of Medicine in collaboration with researchers from DSM Nutritional Products, state that epidemiological studies have demonstrated the benefits of dietary flavonoid intake. These may be related to improved endothelial function.
Blood flow in the arm, so-called brachial artery flow-mediated dilation (FMD), was measured by vascular ultrasound at baseline, and again after two hours after an initial dose of EGCG (300 mg) or placebo, and after two weeks of supplementation with EGCG (two 150 mg doses per day) or placebo. Before being crossed-over to the other intervention, the subjects underwent a one-week washout period.
Supplementation with the green tea extract was found to improve FMD from 7.1 to 8.6 per cent two hours after the initial 300 milligram dose, but was not significantly improved when measurements were taken 14 hours after the end of the two weeks of supplementation.
Blood levels of EGCG mirrored the vascular function, said the researchers, increasing from 2.6 to 92.8 nanograms per millilitre after the initial 300 mg dose, but returning approximately to baseline levels after two weeks (3.4 ng/ml).
The results add to an ever-growing body of science linking consumption to a wide range of health benefits, including lower risk of certain cancers, increased weight loss, improved heart health, and protection against Alzheimer's.
Which means that the healthy benefits of green tea can only be had through continuous intake. I think that's a better alternative to a lifetime of medication.
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Benefits
Green tea has been used in China for thousands of years for its health-preserving and revitalizing power. Modern science has identified powerful antioxidants in green tea called polyphenols. One group of polyphenols called catechins is particularly potent and is highly effective at neutralizing free radicals at the cellular level. Catechins support healthy cell function while providing antioxidant protection to critical cell structures such as DNA. Clinical studies show catechins interfere with the production of certain enzymes involved in cell damage. Additionally, catechins have been demonstrated to cause a thermogenic effect that enhances the bodys metabolic rate. Tegreen 97 ® from Pharmanex is a proprietary, highly concentrated extract of the catechins found in green tea. Tegreen 97 ® is one of the most potent antioxidant supplements on the market with a 97 percent polyphenol content, 65% catechins. Each Tegreen 97 ® capsule contains the catechin equivalent of approximately seven cups of green tea and is 99.5 percent caffeine free.
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