Tuesday, July 28, 2009

Ginkgo biloba and donepezil: a comparison in the treatment of Alzheimer's dementia in a randomized placebo-controlled double-blind study


The Ginkgo biloba special extract EGb 761 seems to produce neuroprotective effects in neurodegenerative diseases of multifactorial origin. There is still debate about the efficacy of Ginkgo biloba special extract EGb 761 compared with second-generation cholinesterase inhibitors in the treatment of mild to moderate Alzheimer's dementia. Our aim is to assess the efficacy of the Ginkgo biloba special extract E.S. in patients with dementia of the Alzheimer type in slowing down the disease's degenerative progression and the patients' cognitive impairment compared with donepezil and placebo.

Our study suggests that there is no evidence of relevant differences in the efficacy of EGb 761 and donepezil in the treatment of mild to moderate Alzheimer's dementia, so the use of both substances can be justified. In addition, this study contributes to establish the efficacy and tolerability of the Ginkgo biloba special extract E.S. in the dementia of the Alzheimer type with special respect to moderately severe stages.

Which simply means that Ginkgo biloba extract is just as effective as donepezil (a drug) in the treatment of Alzheimer's dementia. ^_^
Pharmanex BioGinkgo™ 27/7 is an exclusive extra strength (50:1) preparation of ginkgo biloba leaf extract for the maintenance of healthy cognitive performance and circulatory health.

Primary Benefits

  • Stimulates memory and concentration*
  • Promotes circulation to the brain, arms, and legs*
  • Natural antioxidant that may help support the antioxidant defense system in fighting free radicals*

What Makes This Product Unique?

  • The only ginkgo biloba product that delivers the maximum concentrations of all active compounds as specified by the German monograph standards
  • Uses a proprietary, patented extraction process to yield the highest concentration of actives
  • Clinically-proven to be safe and effective


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