Treatment with 'friendly' bacteria could counter autism in children
PROBIOTIC bacteria given to autistic children improved their concentration and behaviour so much that medical trials collapsed because parents refused to accept placebos, a scientist revealed yesterday.
The effect of the bacteria was so pronounced that some of the parents taking part in what was supposed to be a blind trial realised their children were taking something other than a placebo.
A number then refused to give their children the placebo when they were due to switch, resulting in the collapse of the trial.
Glenn Gibson, a microbiologist who ran the study of 40 autistic children aged between four and eight, said this meant it was difficult to draw any firm conclusions and he is planning to carry out further research.
However, he said parents had told him the probiotic bacteria was having a beneficial effect, resulting in "better concentration and better behaviour".
One parent said it was "heartbreaking" to have to stop their child taking it.
"It was really challenging for us and the parents. I'd really like to go back to it and do it in a better way, with perhaps more professional help from people who know how to deal with autistic children," said Prof Gibson.
"The trial ultimately failed because of the large number of drop-outs. About half the kids dropped out. Some of the parents worked out their child was on the test and didn't want to move on to the placebo."
Autistic children often suffer bowel conditions and Prof Gibson said a previous study had found high levels of a "bad" bacteria called clostridia in the gut.
"If your gut is not behaving yourself, you feel rough," Prof Gibson said.
The clinical trial was so successful it had to be cancelled when parents refused to switch to placebo when they realized that the child was taking more than a placebo because of the profound changes. How's that for convincing evidence? Unfortunately, the trial was cancelled (due to its success), but the results are impressive, nonetheless.
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